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"Protective Mechanism of CyanthOx™ Against Hydrogen Peroxide-Induced Oxidative Damage in Adult Retinal Pigment Epithelial-19 Cells".

New Study: StemXR™CyanthOx™

New Study: Cellregen's StemXR™ key ingredient CyanthOx™ Redefines Eye Health Antioxidants

We are excited to announce the findings from a groundbreaking study published in the journal Antioxidants, titled "Protective Mechanism of CyanthOx™ Against Hydrogen Peroxide-Induced Oxidative Damage in Adult Retinal Pigment Epithelial-19 Cells". This research is a major leap forward in our understanding of the power of natural antioxidants to combat oxidative stress in retinal health, which is crucial for preventing a range of retinal conditions. The study centers on CyanthOx™, a potent proanthocyanidins extract derived from sea buckthorn, known for being one of the most powerful plant-based antioxidants discovered to date.

The Power of CyanthOx™

The focus of this research is to explore how CyanthOx™, with its high concentration of sea buckthorn proanthocyanidins, safeguards the retinal pigment epithelium from oxidative stress. Utilizing a model of oxidative damage in adult retinal pigment epithelial cells triggered by hydrogen peroxide, the study delves into the protective capabilities of CyanthOx™.

Core Discoveries of the Study

  • Oxidative Stress Reduction: CyanthOx™ significantly lowered levels of malondialdehyde, a primary indicator of lipid peroxidation, thereby reducing oxidative stress. It also boosted the activity of key antioxidant enzymes like superoxide dismutase and increased glutathione levels.
  • Enhanced Cell Health: At an optimal dose of 100 µg/mL, CyanthOx™ not only enhanced cell survival and movement but also maintained normal cellular structure, showcasing its strong protective properties.
  • Activation of Protective Pathways: The study unveiled CyanthOx™’s role in activating the Nrf2/HO-1 pathway, crucial for defending against oxidative harm and improving cellular detox processes.
  • Superiority Over Other Antioxidants

    This study builds upon earlier research, demonstrating that sea buckthorn proanthocyanidins are up to 5.3 times more effective than bilberry anthocyanins. In controlled experiments with rabbits, these proanthocyanidins markedly enhanced photopic electroretinogram responses, crucial for assessing visual health.

Implications for the Future

The results highlight CyanthOx™ as a leading contender in the development of advanced eye health supplements. Its unparalleled potency makes it a superior choice over traditional options like bilberry anthocyanins and other known antioxidants such as grapeseed and pine bark extracts.

CyanthOx™ has also shown to boost cellular regeneration by over 40%, positioning it as a key ingredient in eye health products aimed at significantly improving defense against oxidative stress and enhancing overall visual function.

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